Does buprenorphine cause mania?
No. Suboxone doesnt cause mania.
In the majority of studies, buprenorphine has been confirmed to be a safe alternative for opioid substitution therapy. The most common CNS adverse effects, according to a review of buprenorphine on the FDA website, were anxiety, depression, sleeplessness, nervousness, and somnolence. Constipation, nausea, vomiting, headache, dizziness, and flu symptoms were also common side effects of buprenorphine on other systems. According to Wiegand5, significant buprenorphine side effects including respiratory depression were more likely to develop in drug-naive juvenile patients or those with a concurrent lung condition such chronic obstructive pulmonary disease. There was no substantial information found in a PubMed search using the keywords buprenorphine and psychosis. However, a search of the terms buprenorphine and hallucination turned up a sequence of five occurrences of reported visual hallucinations, one of which occurred after epidural buprenorphine injection. In that example, the epidural buprenorphine dose was 1,159 g. Another case report showed auditory hallucinations in a patient who got buprenorphine following a hemorrhoidectomy to reduce pain. As a result, we'd want to call attention to buprenorphine's psychotic side effects, which, while extremely uncommon, can be quite disturbing.